2016 ACVIM Forum Research Abstract Program

In this population of dogs with CKD the prevalence of dogs with positive urine culture was 18.1%. The most frequently observed diagnosis associated with a positive culture was SBU. Increasing IRIS stage of CKD was not found to be associated with a higher frequency of any particular diagnosis. E. coli was the most commonly observed isolate. Despite the rigorous criteria for defining SBU, pyelonephritis, and UTI in the current study, it is possible that some patients were incorrectly categorized. Prospective research is needed to determine if antibiotic therapy is indicated in dogs with CKD and SBU. Additionally, renal biomarkers may allow for better characterization of patients with SBU and occult pyelonephritis and improve antibiotic stewardship. The aim of this study was to report combined experience of two institutions placing subcutaneous ureteral bypass systems (SUBs). We compared our data to historical data from cats with ureteral stents for ureteral obstruction. Hypotheses included 1) Patients with SUBs would have the same or better 7-14 day and 3-4 month post-operative creatinine as historic ureteral stent patients, 2) SUB patients would experience the same or improved peri-operative, post-operative and recurrent urinary tract infection rates as ureteral stent cats, 3) clinical signs related to implants would be similar or better with the SUB system versus ureteral stenting.