2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018

These findings suggest, that in the context of leptospirosis, overexpression of endothelial ICAM-1 may be associated with the development of pulmonary hemorrhage. We examined data from a regional human pediatric medical center (2010) (2011) (2012) (2013) (2014) (2015) (2016) , and from a veterinary clinical laboratory and a veterinary reference laboratory (2002) (2003) (2004) (2005) (2006) (2007) (2008) (2009) (2010) (2011) (2012) (2013) (2014) (2015) (2016) (2017) . We focused on urinary isolates from pediatric and canine populations to compare resistance patterns most common in each and to examine for the emergence of similar resistance patterns. We examined the resistance of E. coli urinary tract isolates to five major classes of antibiotics from dogs and children. We further examined the prevalence of phenotypic resistance patterns to combinations of drug classes.