Selected article for: "crossover design and randomized crossover design"
Title: 2015 ACVIM Forum Research Abstract Program
  • Document date: 2015_5_27
    • ID: 3pnuj5ru_248
    Snippet: Seven healthy adult mixed breed dogs were enrolled in a randomized crossover design study consisting of a paired IV/oral crossover, with a 1-week washout period between treatments. Dogs were given 25 mg/kg metformin IV or 20 mg/kg metformin orally. Before administration and at time 0.33, 0.57, 1, 1. 33, 1.67, 2, 2.5, 3, 4, 5, 6, 7, 8, 10, 12, 15, 18, 24, 30, 36, 48 and 72 hours after administration blood samples were collected via indwelling cath.....
    Document: Seven healthy adult mixed breed dogs were enrolled in a randomized crossover design study consisting of a paired IV/oral crossover, with a 1-week washout period between treatments. Dogs were given 25 mg/kg metformin IV or 20 mg/kg metformin orally. Before administration and at time 0.33, 0.57, 1, 1. 33, 1.67, 2, 2.5, 3, 4, 5, 6, 7, 8, 10, 12, 15, 18, 24, 30, 36, 48 and 72 hours after administration blood samples were collected via indwelling catheter for drug analysis. Metformin serum concentrations were determined using a validated LC-MS/MS method.

    Search related documents:
    Co phrase search for related documents
    • administration blood and drug analysis: 1, 2
    • administration blood and LC MS MS method: 1
    • administration blood and serum concentration: 1, 2
    • administration blood and washout period: 1, 2
    • breed dog and design study: 1
    • design study and drug analysis: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • design study and serum concentration: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
    • design study and treatment washout period: 1, 2, 3
    • design study and washout period: 1, 2, 3, 4, 5, 6
    • drug analysis and washout period: 1
    • IV oral crossover and washout period: 1
    • LC MS MS method and validate LC MS MS method: 1
    • serum concentration and treatment washout period: 1
    • serum concentration and washout period: 1
    • treatment washout period and washout period: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14