2015 ACVIM Forum Research Abstract Program

Although not all cats became/remained euthyroid during the study period, management with y/d Ã’ Feline reduced TT4 without decreasing GFR or EMD. Compared with sCr, SDMA may be a better marker of renal excretory function in hyperthyroid cats. Ketones, including beta hydroxybutyrate (BHB), are produced in conditions of chronic negative energy balance and/or decreased glucose utilization. Little is known, however, about whether serum BHB concentrations increase in catabolic states other than diabetes mellitus in cats. The primary aim of this study was to determine if serum BHB concentrations are increased in cats with three potentially catabolic disease states: chronic kidney disease (CKD), hyperthyroidism (HT), and hepatic lipidosis (HL). Secondary aims were to determine if serum BHB concentrations are correlated with other clinical variables, and to determine if serum BHB concentrations are correlated with urine ketone measurement by dipstick, which primarily measures acetoacetate.