Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_321
Snippet: Twenty-two dogs with a total of 109 ACTH stimulation tests were evaluated. Use of a baseline cortisol concentration cutoff of 3.2 lg/dL or greater resulted in a negative predictive value of 100% that the ACTH-stimulated cortisol concentration would indicate excessive suppression. However, 21.8% of the ACTH stimulation tests with baseline concentrations above this cut-off had post-stimulation cortisol concentrations that were less than baseline. I.....
Document: Twenty-two dogs with a total of 109 ACTH stimulation tests were evaluated. Use of a baseline cortisol concentration cutoff of 3.2 lg/dL or greater resulted in a negative predictive value of 100% that the ACTH-stimulated cortisol concentration would indicate excessive suppression. However, 21.8% of the ACTH stimulation tests with baseline concentrations above this cut-off had post-stimulation cortisol concentrations that were less than baseline. In addition, there was substantial overlap of the baseline cortisol concentrations when compared to the clinician's decision regarding trilostane dose.
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