Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_322
Snippet: There exists a baseline cortisol concentration in this population of patients that can predict an ACTH-stimulated cortisol greater than 2.0 ug/dL. However, this cut-off does not guarantee an acceptable adrenal reserve capacity or control of clinical signs, therefore routine use of baseline cortisol as the sole monitoring diagnostic in trilostane-treated PDH patients cannot be recommended. Hypertension is a common finding in older cats. A variety .....
Document: There exists a baseline cortisol concentration in this population of patients that can predict an ACTH-stimulated cortisol greater than 2.0 ug/dL. However, this cut-off does not guarantee an acceptable adrenal reserve capacity or control of clinical signs, therefore routine use of baseline cortisol as the sole monitoring diagnostic in trilostane-treated PDH patients cannot be recommended. Hypertension is a common finding in older cats. A variety of underlying reasons for hypertension have been suggested including hyperthyroidism, where it is estimated around 20% are hypertensive at diagnosis. The literature to date has predominantly consisted of studies using Doppler technology where diastolic blood pressures are not determined. In addition these studies did not use an age matched control group to assess the data.
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