2015 ACVIM Forum Research Abstract Program

The data shows that as a group older cats and hyperthryoid cats have similar blood pressures with a similar percentage of cats being considered at risk of target organ damage (61% of control cats and 67% of hyperthyroid cats based on systolic blood pressure) however in the hyperthyroid group there is a higher percentage of cats with severe risk of target organ damage. Diastolic risk of target organ damage was more common in the hyperthyroid group (29% vs. 17%), though generally only moderate or mild. The aim of this study was to evaluate epidemiological characteristics of adrenal tumors (AT) in dogs. A retrospective study was conducted based on clinical records considering age, breed, sex, clinical signs, laboratorial findings, hormonal tests, medical or surgical treatment, histological findings and survival from dogs diagnosed with AT between January 2012 and November 2014 at the Naya Especialidades Veterinary Clinics. Among 49 dogs diagnosed with AT, 37 (76%) were female and the mean age was 11.3 AE 2.5 years. Forty-four (89,79%) dogs were purebred, mainly Shih Tzu (11), Lhasa apso (6) and Dachshund (6). The mean body weight was 12.37 AE 11.6 kg (Median 7 kg; range, 3.4 to 60 kg). Body weight was ≤ 10 kg in 69.4% of dogs. Polyuria, polydipsia (59.2%), polyphagia (59.2%) and abdominal distension (36.7%) were the most frequent clinical signs. Increased ALP (86.7%) and ALT (40%), hyperlipidemia (45.6%), low urinary density (57.5%), thrombocytosis (30.2%) and hypertension (51.4%) were reported. A diagnosis of adrenal-dependent hyperadrenocorticism on the basis of nonsuppressed serum cortisol concentration by use of an LDDS test or an inappropriately high serum cortisol concentration after ACTH stimulation was observed in 48,5% and 38,8%, respectively. Forty-eight per cent of dogs had right AT, 36.7% left and 22.4% bilateral. Adrenalectomy was performed on 20 dogs (40,8%). The histological findings revealed adenoma in 65%, carcinoma in 20% and pheocromocitoma in 15% of dogs. Twenty dogs were treated only with trilostane and 8 had no therapy. Of the 49 dogs, 45 (92%) are still alive in a 2 years follow up. Primary AT incidence may be increasing, especially in small dogs (< 10 kg). Cortex adrenal tumors are more common, but some animals may be asymptomatic and have negative LDDS and ACTH stimulation test. Therapy with adrenalectomy or trilostane should be encouraged. Pancreatitis is the most common exocrine pancreatic disease in dogs and has a multifactorial etiology. Endocrine abnormalities and hyperlipidemia are considered risk factors. The aim of this study was to investigate the association of acute pancreatitis with diabetes mellitus (DM), confirmed hyperadrenocorticism (HAC), possibility of HAC (adrenomegaly on ultrasound without previous diagnosis of HAC), hypothyroidism (HYPOT), hypertriglyceridemia (HYPERTRI) and hypercholesterolemia (HYPER CHOL). A retrospective study was performed in dogs admitted to a private veterinary hospital in São Paulo, Brazil. Dogs with symptoms and sonographic diagnosis of pancreatitis in the years 2012 and 2013 (group 1, n = 50) and control group dogs without sonographic pancreatic alterations, but with chronic kidney disease from 2013 to 2014 (group 2, n = 41) were studied. The past history was evaluated for the diagnosis of diabetes (blood glucose > 200 mg/dL, positive glycosuria), HAC (cortisol after low dose dexamethasone > 1.4 ug/dL or post ACTH > 21 ug/dL) and HYPOT (thyroid-stimulating hormone > 0