Selected article for: "blood contamination and ck value"
Title: 2016 ACVIM Forum Research Abstract Program
  • Document date: 2016_5_31
    • ID: 2y1y8jpx_125
    Snippet: Jourdan Brune, Annie Chen-Allen. Washington State University, Pullman, WA, USA Cerebrospinal fluid (CSF) analysis is regularly performed in patients with neurological disease but iatrogenic blood contamination can distort results. The effects of iatrogenic blood contamination on canine CSF lactate dehydrogenase (LD) and creatine kinase (CK) total and isoenzyme activity have not been previously evaluated. CK exists as 3 isoenzymes (CK-MM, CK-MB, C.....
    Document: Jourdan Brune, Annie Chen-Allen. Washington State University, Pullman, WA, USA Cerebrospinal fluid (CSF) analysis is regularly performed in patients with neurological disease but iatrogenic blood contamination can distort results. The effects of iatrogenic blood contamination on canine CSF lactate dehydrogenase (LD) and creatine kinase (CK) total and isoenzyme activity have not been previously evaluated. CK exists as 3 isoenzymes (CK-MM, CK-MB, CK-BB) and LD exists as 5 isoenzymes (LD1-5) in both serum and CSF. Investigating the effects of blood contamination on total LD and CK and their isoenzyme activity could allow clinicians to better interpret the diagnostic and prognostic value of LD and CK isoenzymes in canine neurologic patients.

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