2016 ACVIM Forum Research Abstract Program

Medical records of 32 dogs diagnosed with all forms of lymphoma, 23 dogs diagnosed with IBD and 28 control dogs, presented to the Centre Hospitalier Universitaire V et erinaire between 2006 and 2014 were retrospectively reviewed. Each blood smear was blindly re-assessed by a board-certified pathologist. A comparison between the following 3 groups: healthy dogs, dogs with IBD and dogs with lymphoma, as well as within the lymphoma group (stages 1,2,3 versus 4/5, sub-stage a versus b, and small versus intermediate/large cells) was performed for the following hematologic parameters: hematocrit, hemoglobin, erythrocyte count, mean corpuscular volume, and mean corpuscular hemoglobin concentration. The total numbers and each specific RBC anomaly were compared between these 3 groups. RBC morphologic anomalies were also categorized by the underlying pathologic process (regenerative anemia, oxidative stress, or other morphologic changes) and compared between the 3 groups.