2016 ACVIM Forum Research Abstract Program

In conclusion, the B. burgdorferi peptides used in the Accuplex 4 BioCD system do not recognize antibodies induced by the commercially available Leptospira spp. vaccines administered in this study. However, lateral flow device manufacturers and laboratories providing B. burgdorferi serological assays have specific sources of peptides that may vary antigenically from those used here and so the results of this study may not be the same for all laboratories. Anaplasma phagocytophilum (AP) is transmitted by Ixodes spp. and is the cause of granulocytic anaplasmosis in many species including dogs, cats, horses, and people. In endemic areas, antibodies against AP are detected in the serum of up to 40% of dogs and some healthy dogs are AP PCR positive. The effect of prednisolone administration on dogs infected with AP after I. scapularis infestation has not been determined.