Title: 2016 ACVIM Forum Research Abstract Program Document date: 2016_5_31
ID: 2y1y8jpx_639
Snippet: Five purpose-bred cats with unremarkable complete blood count, serum biochemistry and urinalyses were utilized. PK study: Each cat received 0.8 mg/kg subcutaneous (SQ) and intravenous (IV) dolasetron in a cross-over manner. Serum samples were obtained via jugular catheter at 0, 0.25, 0.5, 1, 2, 4, 8, 12, 24, 36 and 48 hours after administration of dolasetron. Dolasetron and the active metabolite hydrodolasetron were measured using liquid chromato.....
Document: Five purpose-bred cats with unremarkable complete blood count, serum biochemistry and urinalyses were utilized. PK study: Each cat received 0.8 mg/kg subcutaneous (SQ) and intravenous (IV) dolasetron in a cross-over manner. Serum samples were obtained via jugular catheter at 0, 0.25, 0.5, 1, 2, 4, 8, 12, 24, 36 and 48 hours after administration of dolasetron. Dolasetron and the active metabolite hydrodolasetron were measured using liquid chromatography/tandem mass spectrometry. Non-compartmental pharmacokinetic analysis was performed. PD study: Subcutaneous dolasetron (0.8 mg/kg or 1.0 mg/kg) or placebo was administered 30 minutes prior to intramuscular administration of 0.44 mg/kg xylazine in a randomized crossover manner. Number of emetic events, lip licks, time to onset of vomiting or visual nausea score were scored by a blinded observer.
Search related documents:
Co phrase search for related documents- blood count and chromatography tandem mass spectrometry: 1
- blood count and complete blood count: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80
- blood count and intramuscular administration: 1
- blood count and jugular catheter: 1, 2
- blood count and liquid chromatography tandem mass spectrometry: 1
- blood count and mass spectrometry: 1, 2, 3, 4
- blood count and pk study: 1, 2, 3
- blood count and serum biochemistry: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24
- blood count and urinalysis serum biochemistry: 1, 2, 3, 4, 5, 6, 7, 8
- blood count and urinalysis serum biochemistry complete blood count: 1, 2, 3, 4, 5, 6, 7, 8
- chromatography tandem and complete blood count: 1
- chromatography tandem and jugular catheter: 1, 2
- chromatography tandem and liquid chromatography tandem mass spectrometry: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- chromatography tandem and liquid chromatography tandem mass spectrometry measure: 1
- chromatography tandem and mass spectrometry: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- chromatography tandem and non compartmental pharmacokinetic analysis: 1
- chromatography tandem and pharmacokinetic analysis: 1, 2, 3
- chromatography tandem and pk study: 1
- chromatography tandem and serum biochemistry: 1, 2
Co phrase search for related documents, hyperlinks ordered by date