2016 ACVIM Forum Research Abstract Program

Pregnancy toxemia was diagnosis in 108 goats. Prevalence of mortality was 5.0% during prepartum and first week of lactation period. There were 26 cases of mortality during prepartum period (96.2% associated with PT) and 28 cases of mortality during the first week of lactation (71.4% associated with PT). Critical cutpoints for predicting mortality during last month of pregnancy and first week of lactation were determined based on the highest sum of sensitivity and specificity every week. Blood concentration above 0.6 mmol/L during week 4 before kidding (sensitivity (Se): 44.7%; specificity (Sp): 86.7%), 3 (Se: 65.4% ; Sp: 82.7%), and 2 (Se: 70.8%; Sp: 76.1%) before kidding, above 1.4 mmol/L during week 1 before kidding (Se: 51.3% ; Sp: 93.5%) and above 1.7 for the first week of lactation (Se: 28.6% ; Sp: 95.0%) were selected as the optimal cutpoints in this study. Presence of treatment during the last month of pregnancy was associated with increased mortality in dairy goat (OR: 11.79, P < 0.01)