Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018 Document date: 2018_10_25
ID: 60ceejq1_640
Snippet: Post-mortem samples of CKCS were collected prospectively though a donation scheme available to owners and veterinarians. Collection was irrespective of disease state or antemortem diagnosis. Clinical information was obtained where possible. Liver, pancreas, kidney and lung were stored as formalin-fixed paraffin-imbedded samples. Tissues were matched by age and histopathologic diagnosis to tissues from non-CKCS breed dogs. Sirius red staining, hig.....
Document: Post-mortem samples of CKCS were collected prospectively though a donation scheme available to owners and veterinarians. Collection was irrespective of disease state or antemortem diagnosis. Clinical information was obtained where possible. Liver, pancreas, kidney and lung were stored as formalin-fixed paraffin-imbedded samples. Tissues were matched by age and histopathologic diagnosis to tissues from non-CKCS breed dogs. Sirius red staining, highlighting fibrosis, was performed and slides digitized for objective analysis. Software analysed for red staining and scored this as a proportion of the tissue volume. Those analysing were blinded to breed and pathologic diagnosis.
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