2015 ACVIM Forum Research Abstract Program

Results are summarized in Table 1 . According to the results of this study, it was possible to observe an inverse correlation between some of the echocardiographic parameters and IL-6 Log , IL-10 Log , TNF-a Log and CRP Log , confirming myocardial involvement in dogs with naturally occurring sepsis. A prospective cross-sectional study was conducted to evaluate the duration of the corrected QT interval (QTc) and QT dispersion from 58 electrocardiographic tracings, from 31 bitches with pyometra compared to 27 healthy bitches, of same breed or size, and similar age, in order to evaluate possible changes, considering that prolonged QT can be related to arrythmia predisposition in humans and animals. QTc was calculated using Bazett's (QTc= QT/√RR) and Fridericia's (QTc=QT/ 3 √RR) equations, with RR and QT intervals obtained from lead II. QT dispersion (Qt max -QT min ) was calculated among 10 leads (I, II, III, aVR, aVL, aVF, rV 2 (CV 5 RL), V 2 (CV 6 LL), V 3 (CV 6 LU) and V 10 at 50 mm/s). QTc was significantly prolonged in pyometra dogs when calculated by Bazett 0 s equation (QTc control =264.5 AE 24.1 ms vs QTc pyom =277.4 AE 21.6 ms; P = 0.038), while QTc calculated by Fridericia 0 s equation and QT dispersion were not significantly different. The prolonged QTc in pyometra dogs, evaluated by Bazett 0 s equation, suggests increased susceptibility to arrhythmias in this group. The lack of difference when using Fridericia 0 s equation must be better evaluated in larger samples, and these variables should be assessed in a prospective study, including the outcome of arrhythmia occurence during and after surgery. Dogs with myxomatous mitral valve disease (MMVD) in Class C of the congestive heart failure (CHF) show clinical signs along the progression of the disease, changes in the size of the heart chambers, rhythm cardiac, heart rate, participation of the autonomic system.