Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_233
Snippet: Starting in June 2010, dog owners were given the option to use a metronomic chemotherapy protocol after completing the suramin/doxorubicin treatment. The metronomic chemotherapy protocol consisted of artemisinin (Holley Pharmaceuticals, Tustin, CA), 100 mg PO q24 h; toceranib phosphate (Palladia, Zoetis, Florham Park, NJ), 2.5 mg/kg PO on Mondays, Wednesdays, and Fridays; and cyclophosphamide, 10 mg/m 2 PO on Tuesdays, Thursdays, and Saturdays. D.....
Document: Starting in June 2010, dog owners were given the option to use a metronomic chemotherapy protocol after completing the suramin/doxorubicin treatment. The metronomic chemotherapy protocol consisted of artemisinin (Holley Pharmaceuticals, Tustin, CA), 100 mg PO q24 h; toceranib phosphate (Palladia, Zoetis, Florham Park, NJ), 2.5 mg/kg PO on Mondays, Wednesdays, and Fridays; and cyclophosphamide, 10 mg/m 2 PO on Tuesdays, Thursdays, and Saturdays. Dogs were on this protocol until development of metastases or death. A CBC, serum chemistry profile, urinalysis and thoracic radiographs were done at each three months visit. Survival time (ST) and disease free interval (DFI) were generated using the Kaplan-Meier method and compared using log rank analysis. A P value of less than 0.05 was considered significant.
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