2015 ACVIM Forum Research Abstract Program

Considering the anesthetic and analgesic protocol used in this study and based on the observed results it can be concluded that UTM alone or in association with OSH does not induce significant changes in serum levels of cortisol, glucose and albumin in the postoperative period. In animals submitted to UTM was found only a slight increase in serum glucose levels at the end of surgery. Introduction: Rapamycin is an antifungal antibiotic agent that has immunosuppressant and anti-cancer properties. By inhibiting mTOR, rapamycin acts as an anti-proliferative and anti-angiogenic agent. The purpose of this pilot study was to determine the blood concentrations of rapamycin achieved following a single dose and multiple oral doses in the dog.