Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_72
Snippet: Results from this pilot study show that apixaban is a safe and effective anticoagulant in cats and should be considered for use in the treatment and prevention of feline ATE. The PK and PD data obtained from this pilot study are necessary for subsequent clinical trials in feline patients with heart disease. Irish wolfhounds (IW) are commonly affected with atrial fibrillation (AF) and dilated cardiomyopathy (DCM). This study reports the long-term .....
Document: Results from this pilot study show that apixaban is a safe and effective anticoagulant in cats and should be considered for use in the treatment and prevention of feline ATE. The PK and PD data obtained from this pilot study are necessary for subsequent clinical trials in feline patients with heart disease. Irish wolfhounds (IW) are commonly affected with atrial fibrillation (AF) and dilated cardiomyopathy (DCM). This study reports the long-term outcome of 52 IW with apparently "lone" AF, compared to an age and gender matched control cohort. IW from Western Europe (n = 1552) underwent physical examination, standard echocardiography and electrocardiography between 5/1990-10/2014 (AV). Dogs were followed longitudinally, and owners reported the date and circumstances of death. Kaplan-Meier survival curves were constructed for both groups, and compared using the Log-Rank (Mantel-Cox) test.
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