2015 ACVIM Forum Research Abstract Program

Serum samples from healthy Greyhounds (n = 16), Greyhounds with diarrhea (n = 30), or a history of thrombotic events (n = 8) were collected at the Ohio State University and Texas A&M University. Serum HCY concentrations (reference interval [RI]: 5.0-22.1 lmol/L) were measured by gas chromatography/ mass spectrometry. Concentrations of cobalamin (RI: 251-908 ng/L) and folate (RI: 7.7-24.4 lg/L) were measured using an automated chemiluminescence assay. Concentration of serum HCY, cobalamin, and folate were compared among the three groups of Greyhounds using an ANOVA or a non-parametric Kruskal-Wallis test, as applicable. Correlation analysis was performed to test for any possible correlation between HYC and the two B vitamins.