Author: Jartti, Tuomas; Smits, Hermelijn H.; Bønnelykke, Klaus; Bircan, Ozlem; Elenius, Varpu; Konradsen, Jon R.; Maggina, Paraskevi; Makrinioti, Heidi; Stokholm, Jakob; Hedlin, Gunilla; Papadopoulos, Nikolaos; Ruszczynski, Marek; Ryczaj, Klaudia; Schaub, Bianca; Schwarze, Jürgen; Skevaki, Chrysanthi; Stenberg-Hammar, Katarina; Feleszko, Wojciech
Title: Bronchiolitis needs a revisit: Distinguishing between virus entities and their treatments Document date: 2018_11_25
ID: 4svg09dt_31
Snippet: Rhinoviruses also directly target airway epithelial cells. RV type A frequently causes lower respiratory tract infection, and RV type C in particular is linked to severe wheezing in infected children. 8, 13, 61 The increased risk of severe RV infection with wheeze in young children with a strong family history of allergy and asthma may be explained by a partial defect in mucosal antiviral innate interferon responses, due potentially to early alle.....
Document: Rhinoviruses also directly target airway epithelial cells. RV type A frequently causes lower respiratory tract infection, and RV type C in particular is linked to severe wheezing in infected children. 8, 13, 61 The increased risk of severe RV infection with wheeze in young children with a strong family history of allergy and asthma may be explained by a partial defect in mucosal antiviral innate interferon responses, due potentially to early allergic airways inflammation ( Figure 4B ).
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