Author: Nasir, Arshan; Caetano-Anollés, Gustavo
Title: A phylogenomic data-driven exploration of viral origins and evolution Document date: 2015_9_25
ID: 49360l2a_49
Snippet: Our phylogenomic reconstructions also show that proto-virocells initially harbored segmented RNA genomes and that proteomes of all seven kinds of viral replicons were enriched in ancient FSFs (Fig. 5C) . Given the massive diversity in replicon type seen in modern viruses, it is likely that all kinds of replication strategies were used in proto-virocells. A logical outcome of this experimentation would be the discovery of many key replication-asso.....
Document: Our phylogenomic reconstructions also show that proto-virocells initially harbored segmented RNA genomes and that proteomes of all seven kinds of viral replicons were enriched in ancient FSFs (Fig. 5C) . Given the massive diversity in replicon type seen in modern viruses, it is likely that all kinds of replication strategies were used in proto-virocells. A logical outcome of this experimentation would be the discovery of many key replication-associated proteins and perhaps DNA itself in the virus world [an idea previously put forward by Forterre (66, 96) ].
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