Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_431
Snippet: Genomic DNA extracts from 20 cobalamin-deficient and 36 normocobalaminemic Shar-Peis were used. Genotyping was performed using two assay sets, 1) the CNV-Eastern assay [16.1 kbduplication] and 2) the CNV_23.759 assay [14.3 kb-duplication] normalized to assay C7orf28B. Copy numbers obtained were compared between cobalamin-deficient and normocobalaminemic Shar-Peis by use of a Mann-Whitney U test. A Fisher's exact test was used and the odds ratios .....
Document: Genomic DNA extracts from 20 cobalamin-deficient and 36 normocobalaminemic Shar-Peis were used. Genotyping was performed using two assay sets, 1) the CNV-Eastern assay [16.1 kbduplication] and 2) the CNV_23.759 assay [14.3 kb-duplication] normalized to assay C7orf28B. Copy numbers obtained were compared between cobalamin-deficient and normocobalaminemic Shar-Peis by use of a Mann-Whitney U test. A Fisher's exact test was used and the odds ratios (OR) calculated to evaluate whether low or high copy numbers of the two duplications are associated with cobalamin deficiency.
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