Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_570
Snippet: AP DNA was amplified from blood of all dogs and all had AP antibodies in serum by multi-analyte SNAP Ã’ research ELISA. Antibodies to AP were detected prior to those detected by the commercially available kit for 6 of 8 dogs. Antibodies to BB were detected only in 6 of 8 dogs and were first detected between 3-6 weeks post-tick attachment, with 4/6 seropositive by day 28. All dogs were seropositive for AP from 31 to 43 weeks by SNAP MA, AP IFA, AP.....
Document: AP DNA was amplified from blood of all dogs and all had AP antibodies in serum by multi-analyte SNAP Ã’ research ELISA. Antibodies to AP were detected prior to those detected by the commercially available kit for 6 of 8 dogs. Antibodies to BB were detected only in 6 of 8 dogs and were first detected between 3-6 weeks post-tick attachment, with 4/6 seropositive by day 28. All dogs were seropositive for AP from 31 to 43 weeks by SNAP MA, AP IFA, APH-1 and APH-4 ELISA with modest declines in seroreactivity post-treatment. In the five dogs that were BB seropositive on week 31, C6 antibody levels declined (by week 43) from 63 to 92% with a mean decline of 81% relative to pre-treatment values. Optical density readings for AP and BB on SNAP MA demonstrated significant decreases between 31-43 weeks however the magnitude of the difference was significantly greater for BB than AP (P < 0.05).
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