Author: Lee, Nak-Hyung; Lee, Jung-Ah; Park, Seung-Yong; Song, Chang-Seon; Choi, In-Soo; Lee, Joong-Bok
Title: A review of vaccine development and research for industry animals in Korea Document date: 2012_7_31
ID: 1c1jd9oz_10
Snippet: For examples, modified live vaccines for avian influenza virus (AIV) have been used in many countries to control AIV infection since killed vaccines are moderately effective but multiple injections are needed to develop protective immunity [12] . Although vaccination is not perfect, it would be the most promising control means for the low pathogenic avian influenza (LPAI) H9N2 to date [12] . Porcine epidemic diarrhea virus (PEDV) is an agent caus.....
Document: For examples, modified live vaccines for avian influenza virus (AIV) have been used in many countries to control AIV infection since killed vaccines are moderately effective but multiple injections are needed to develop protective immunity [12] . Although vaccination is not perfect, it would be the most promising control means for the low pathogenic avian influenza (LPAI) H9N2 to date [12] . Porcine epidemic diarrhea virus (PEDV) is an agent causing severe entero-pathogenic diarrhea in pigs, which leads to significant economic losses in Asia. PEDV strain DR13, a field isolate, was attenuated by serially passing the virus on Vero cells and tested for its virulence in piglets and sows. Vero cell-adapted virus showed reduced pathogenicity and induced protective immunity in pigs, indicating that this attenuated virus may be a vaccine candidate [13] .
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