Author: Ivanova, Elena; Berger, Audrey; Scherrer, Anne; Alkalaeva, Elena; Strub, Katharina
Title: Alu RNA regulates the cellular pool of active ribosomes by targeted delivery of SRP9/14 to 40S subunits Document date: 2015_3_11
ID: 64cnoqpi_6
Snippet: SRP9/14 was discovered as a subunit of SRP, which binds the Alu portion of 7SL RNA. The protein is required for the elongation arrest activity of SRP, which ensures efficient protein translocation into the endoplasmic reticulum (ER) in mammalian cells (14) . In addition to forming complexes with 7SL RNA and Alu RNA, the majority of SRP9/14 exists as a free protein in primate cells (11) ......
Document: SRP9/14 was discovered as a subunit of SRP, which binds the Alu portion of 7SL RNA. The protein is required for the elongation arrest activity of SRP, which ensures efficient protein translocation into the endoplasmic reticulum (ER) in mammalian cells (14) . In addition to forming complexes with 7SL RNA and Alu RNA, the majority of SRP9/14 exists as a free protein in primate cells (11) .
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