2015 ACVIM Forum Research Abstract Program

While vomiting was not noted during the equilibration period, during the antibiotic administration period, 7 SF68 cats and 6 placebo cats vomited at least once. However, the total number of vomiting episodes during the antibiotic administration period were not significantly different between the groups and vomiting resolved in all cats after stopping the antibiotic. During the antibiotic period, while a stool with a FS of ≥5 was detected at least once in 11 SF68 cats and 12 placebo cats, a FS of ≥ 6 was detected in only 8 SF68 cats (61.5%) in contrast to 12 placebo cats (85.7%) and a FS of 7 was only detected in 3 placebo cats (21.4%). When percentages of samples with different FS were compared between the groups in the antibiotic administration period, it was shown that cats in the placebo group (61 of 95 samples; (68.4%) had a greater number (P = 0.006) of samples with a FS ≥5 than the SF68 group (42 of 96 samples; 43.8%) and samples with a FS = 7 were only detected in the placebo group (7 of 95 samples; P = 0.007). Percentages of cats with samples with FS ≥5 decreased in both groups in the post-antibiotic period (SF68 = 15 of 40 samples [37.5%]; Placebo cats = 23 of 42 samples [54.7%]) but the difference between groups was not significant (P = 0.1283). Overall, attitude and hydration was normal for all cats over the course of the study.