Author: Alba Grifoni; John Sidney; Yun Zhang; Richard H Scheuermann; Bjoern Peters; Alessandro Sette
Title: Candidate targets for immune responses to 2019-Novel Coronavirus (nCoV): sequence homology- and bioinformatic-based predictions Document date: 2020_2_20
ID: 8p1agcm2_6
Snippet: B cell epitopes derived from SARS-CoV, were mapped back to a SARS-CoV reference sequence using the IEDB's Immunobrowser tool (5) . This tool combines all records available along a reference sequence and produces a Response Factor (RF) score that accounts for the positivity rate (how frequently a residue was found in a positive epitope) and the number of records (how many independent assays are reported). Dominant regions were identified consideri.....
Document: B cell epitopes derived from SARS-CoV, were mapped back to a SARS-CoV reference sequence using the IEDB's Immunobrowser tool (5) . This tool combines all records available along a reference sequence and produces a Response Factor (RF) score that accounts for the positivity rate (how frequently a residue was found in a positive epitope) and the number of records (how many independent assays are reported). Dominant regions were identified considering residues stretches where the RF score was ≥ 0.3.
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