Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_939
Snippet: This GWAS identified several regions in the horse genome that are associated with EHM in the study population, and should be further explored. Understanding how host variation contributes to EHM will enhance our knowledge of disease pathophysiology, improving treatment of individual cases and management of outbreaks. Maternal antibodies have been reported to exert a significant inhibitory effect (maternal antibody interference) on the immune resp.....
Document: This GWAS identified several regions in the horse genome that are associated with EHM in the study population, and should be further explored. Understanding how host variation contributes to EHM will enhance our knowledge of disease pathophysiology, improving treatment of individual cases and management of outbreaks. Maternal antibodies have been reported to exert a significant inhibitory effect (maternal antibody interference) on the immune response of foals to various antigens contained in commercial vaccines. Based on previous information, it has been recommended that primary immunization of foals born to vaccinated mares should not begin prior to 6 months of age following the decline of maternally-derived antibodies. The objective of this study was to evaluate the WNV antibody response in foals (with and without WNV maternal antibody) following vaccination with Vetera â VEWT+WNV with proprietary adjuvant Carbimmune â .
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