Title: 2016 ACVIM Forum Research Abstract Program Document date: 2016_5_31
ID: 2y1y8jpx_233
Snippet: A significant dose dependent decrease in the mean (AESEM) post AST serum cortisol was observed (placebo 365 AE 13 nmol/L, CA 12.5 mg 347 AE 13 nmol/L, CA 25 mg 335 AE 13 nmol/L, CA 37.5 mg 326 AE 13 nmol/L, CA 50 mg 308 AE 13 nmol/L). There was a significant (P < 0.05) between-week variability in post AST serum cortisol in the placebo and 25 mg and 37.5 mg CA groups. The overall variability in the post AST serum cortisol concentrations was attrib.....
Document: A significant dose dependent decrease in the mean (AESEM) post AST serum cortisol was observed (placebo 365 AE 13 nmol/L, CA 12.5 mg 347 AE 13 nmol/L, CA 25 mg 335 AE 13 nmol/L, CA 37.5 mg 326 AE 13 nmol/L, CA 50 mg 308 AE 13 nmol/L). There was a significant (P < 0.05) between-week variability in post AST serum cortisol in the placebo and 25 mg and 37.5 mg CA groups. The overall variability in the post AST serum cortisol concentrations was attributed to the individual dog (31%), random unexplained variability (31%), dose of CA (16%), age (15%), body weight (4%), and timing of treatment (3%).
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