Title: 2016 ACVIM Forum Research Abstract Program Document date: 2016_5_31
ID: 2y1y8jpx_375
Snippet: Six dogs were given ASA 1 mg/kg/day and placebo, clopidogrel 2 mg/kg/day and placebo, or a combination of both drugs, for 1 week each. Drugs were given in a randomized crossover design (Latin square). Each dog was randomized to one of the three treatments in three different phases such that each dog received each treatment. Investigators were blinded to the treatments. A washout period of 2 weeks occurred between phases. Blood samples were collec.....
Document: Six dogs were given ASA 1 mg/kg/day and placebo, clopidogrel 2 mg/kg/day and placebo, or a combination of both drugs, for 1 week each. Drugs were given in a randomized crossover design (Latin square). Each dog was randomized to one of the three treatments in three different phases such that each dog received each treatment. Investigators were blinded to the treatments. A washout period of 2 weeks occurred between phases. Blood samples were collected on days 0 and 7 of each phase, and analyzed using MP (adenosine diphosphate [ADP], arachidonic acid [AA], collagen [COL] agonists), PFA (P2Y, COL-ADP, COL-Epinephrine [EPI] cartridges), and PW (ADP, AA, COL agonist tubes) using the two hematology analyzers.
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