2016 ACVIM Forum Research Abstract Program

In units of pRBCs, leukoreduction markedly influenced some eicosanoid concentrations. In general, removal of platelets and white cells tended to decrease production of most eicosanoids during storage. For some eicosanoids, however, this effect was counteracted by the passage of blood through the leukoreduction filter, which lead to marked increases in eicosanoid levels in units of pRBCs prior to storage. Further studies will be needed to determine what impact the complex effects of leukoreduction on eicosanoids in stored pRBCs will have on the incidence of transfusion reactions. Dog Erythrocyte Antigen (DEA) 5 is a red cell membrane receptor, and is one of the six blood groups that have been described having clinical implications 1,2 . Up until recently, blood typing was unavailable for this antigen. Previous supplies of the DEA 5 antisera had been exhausted, and the ability to create more was seriously hindered. A novel antisera was recently discovered, bringing back the ability to accurately blood type for the DEA 5 antigen.