Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_139
Snippet: Forty Botucatu rabbits were randomized in four experimental groups. Animals of all groups received doxorubicin (1 mg/kg) intravenously twice a week for 6 weeks. Groups were named G1 (n = 10): doxorubicin, G2 (n = 10): doxorubicin + carvedilol (6.25 mg/Kg), G3 (n = 10): doxorubicin + cyclosporin A (4 mg/ Kg) and G4 (n = 10): doxorubicin + sildenafil (1.8 mg/Kg). The drugs other than doxorubicin were given orally, once a day. Echocardiographic eval.....
Document: Forty Botucatu rabbits were randomized in four experimental groups. Animals of all groups received doxorubicin (1 mg/kg) intravenously twice a week for 6 weeks. Groups were named G1 (n = 10): doxorubicin, G2 (n = 10): doxorubicin + carvedilol (6.25 mg/Kg), G3 (n = 10): doxorubicin + cyclosporin A (4 mg/ Kg) and G4 (n = 10): doxorubicin + sildenafil (1.8 mg/Kg). The drugs other than doxorubicin were given orally, once a day. Echocardiographic evaluations were performed before the first and after the last doxorubicin administration. The statistical analysis was performed by analysis of variance followed by Tukey 0 s test.
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