2015 ACVIM Forum Research Abstract Program

Dogs without diabetes mellitus were prospectively enrolled into one of three groups: dogs with AP, sick dogs without AP, and fasted dogs. Dogs with AP (43) were enrolled if they had vomiting, diarrhea, or anorexia and ultrasonographic findings consistent with AP including an enlarged, irregular, hypoechoic pancreas and hyperechoic mesentery or an increased pancreatic lipase immunoreactivity (PLI>200 mcg/L). Sick dogs without AP (71) were enrolled if they had vomiting, diarrhea, or anorexia and a normal pancreatic ultrasound or a PLI≤200 mcg/L. Dogs fasted for 12 hours were enrolled if they had no vomiting, diarrhea, or anorexia (42). BOHB was measured on whole blood with a portable ketone-meter. The Kruskal Wallis test was performed to confirm that BOHB was significantly different in the three groups (P = 0.0001). Pairwise comparisons were performed using the Mann-Whitney test and Bonferroni corrected p-values are reported.