Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_659
Snippet: The range of serum cystatin C for each of three groups was determined. The healthy group ranged from 899 to 1627 ng/mL; the early disease group ranged from 832 to 1949 ng/mL and the late disease group ranged from 1202 to 2475 ng/mL. This data suggests that cats with early disease will be hard to differentiate from either the healthy group or the late stage disease group. Therefore in this study serum cystatin C does not appear to be better than s.....
Document: The range of serum cystatin C for each of three groups was determined. The healthy group ranged from 899 to 1627 ng/mL; the early disease group ranged from 832 to 1949 ng/mL and the late disease group ranged from 1202 to 2475 ng/mL. This data suggests that cats with early disease will be hard to differentiate from either the healthy group or the late stage disease group. Therefore in this study serum cystatin C does not appear to be better than serum creatinine at classifying kidney disease. These findings are in agreement with the work published by Martin et al. (Martin et al. Revue de Medicine Veterinaire, Vol. 153 p. 305-310, 2002) who recommended that cystatin C should not be used to diagnose kidney failure in cats. Meropenem, a second carbapenem antimicrobial agent with broad spectrum activity, is used in treating sepsis and resistantbacterial infections in veterinary medicine. The objective of this study is identifying the pharmacokinetics of meropenem in dogs receiving intermittent hemodialysis (IHD) and determining proper dose for the patients with renal failure receiving IHD.
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