2015 ACVIM Forum Research Abstract Program

EFFECT OF SINGLE-DOSE TREATMENT WITH SYN-THETIC GHRELIN ON CANINE ANOREXIC PATIENTS: A PRELIMINARY STUDY. Daigo Azakami 1 , Eri Onozawa 1 , Katsumi Ishioka 1 , Masahiro Miyabe 1 , Takeshi Hanada 2 , Yujiro Hayashi 2 , Noboru Murakami 3 , Toshinori Sako 1 . 1 Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan, 2 Asubio Pharma Co, Ltd, Kobe, Hyogo, Japan, 3 University of Miyazaki, Miyazaki, Miyazaki, Japan Ghrelin, a peptide hormone produced in the stomach, is known to have physiological and pharmacological actions on stimulating appetite in humans. In veterinary medicine, physiological effects of ghrelin in healthy dogs have been established; however, clinical application of ghrelin has not ever been reported. Here, to investigate the potential clinical use of ghrelin in dogs, we performed a preliminary study of single-dose treatment with synthetic canine ghrelin on clinically anorexic dogs.