Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_747
Snippet: Esther Bijsmans 1 , Rosanne Jepson 1 , Henry Pratt 2 , Hattie Syme 1 , Jonathan Elliott 1 , Ludovic Pelligand 1 . 1 Royal Veterinary College, London, UK, 2 ABS Laboratories Ltd., Welwyn Garden City, UK Amlodipine is the first-line antihypertensive agent used in cats, and a dose of 0.625-1.25 mg/cat/day is recommended. In human medicine the recommendation exists to initiate a more aggressive antihypertensive plan in patients with severe hypertensi.....
Document: Esther Bijsmans 1 , Rosanne Jepson 1 , Henry Pratt 2 , Hattie Syme 1 , Jonathan Elliott 1 , Ludovic Pelligand 1 . 1 Royal Veterinary College, London, UK, 2 ABS Laboratories Ltd., Welwyn Garden City, UK Amlodipine is the first-line antihypertensive agent used in cats, and a dose of 0.625-1.25 mg/cat/day is recommended. In human medicine the recommendation exists to initiate a more aggressive antihypertensive plan in patients with severe hypertension. In cats, monotherapy with amlodipine is standard practice with dose adjustment used to achieve control. The aim of this study was to investigate whether the dose of amlodipine required to control blood pressure adequately is dependent on individual variation in drug pharmacokinetics or pharmacodynamics.
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