Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_90
Snippet: TVA morphology was variable. Alterations of these structures might influence phenotypic heterogeneity of feline cardiomyopathy and merits further study. The urine aldosterone to creatinine ratio (UAldo:C), using a 'spot' sample has been correlated to the 24-hour urine aldosterone excretion in the dog. Evaluation of the UAldo:C can be used to assess the status of a patient's renin-angiotensin-aldosterone system (RAAS). Aldosterone, a major effecto.....
Document: TVA morphology was variable. Alterations of these structures might influence phenotypic heterogeneity of feline cardiomyopathy and merits further study. The urine aldosterone to creatinine ratio (UAldo:C), using a 'spot' sample has been correlated to the 24-hour urine aldosterone excretion in the dog. Evaluation of the UAldo:C can be used to assess the status of a patient's renin-angiotensin-aldosterone system (RAAS). Aldosterone, a major effector molecule of RAAS, has been associated with perpetuation and progression of heart failure. Monitoring of the UAldo:C may help guide pharmacotherapy and determine which patient's may benefit from mineralocorticoid receptor blockade. The UAldo:C in 34 normal, 1-6 year old dogs in the authors' laboratory is 0.40 AE 0.21 lg/g. Only one dog had a UAldo:C greater than 1.0.
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