2016 ACVIM Forum Research Abstract Program

With the re-introduction of a novel anti-DEA 5 reagent, a more complete profile of canine blood types can be achieved. This can result in better clinical decision making regarding transfusion in the canine patient, and therefore better outcomes, including the avoidance of delayed transfusion reactions when a DEA 5 incompatibility exists. Nonregenerative immune-mediated anemia (NRIMA) is a common hematologic disorder in dogs. Because the bone marrow of the affected dogs shows erythroid hyperplasia and/or erythroid maturation arrest, it has been recognized as immune-mediated destruction of erythroid precursor cells. A variety of immunosuppressive agents have been used in the treatment of this disease, but information regarding the therapeutic efficacy is limited due to the lack of prospective research. The aim of this pilot study was to assess the treatment outcome to the pre designed immunosuppressive regimen including corticosteroids, cyclosporine and mycophenolate mofetil.