Selected article for: "BAL fluid and bronchoalveolar lavage BAL fluid"
Title: 2016 ACVIM Forum Research Abstract Program
  • Document date: 2016_5_31
    • ID: 2y1y8jpx_657
    Snippet: Minocycline (4 mg/kg) was administered via the intragastric route to 6 healthy adult horses every 12 hours for a total of 5 doses. Minocycline concentrations were measured in plasma, pulmonary epithelial lining fluid (PELF), and bronchoalveolar lavage (BAL) cells via liquid chromatography mass spectrometry at multiple time points over a 96 h time period. Pharmacokinetic variables were determined after the last dose using a noncompartmental approa.....
    Document: Minocycline (4 mg/kg) was administered via the intragastric route to 6 healthy adult horses every 12 hours for a total of 5 doses. Minocycline concentrations were measured in plasma, pulmonary epithelial lining fluid (PELF), and bronchoalveolar lavage (BAL) cells via liquid chromatography mass spectrometry at multiple time points over a 96 h time period. Pharmacokinetic variables were determined after the last dose using a noncompartmental approach. Comparison of minocycline concentrations between sampling sites was done using a Friedman repeated measures ANOVA and significance was set at P < 0.05.

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