Title: 2016 ACVIM Forum Research Abstract Program Document date: 2016_5_31
ID: 2y1y8jpx_735_1
Snippet: nity, etc.), a mixed model two way ANOVA with repeated measures was used. In measuring the humoral immune response to the WNV component of the vaccine, results showed a significant (P < 0.05) increase in WNV IgG titers in vaccinated ponies compared to non-vaccinated saline controls. Measurement of CMI responses by flow cytometry showed a significant (P < 0.05) increase in the percentage of WNV-specific interferon-gamma producing cells from the va.....
Document: nity, etc.), a mixed model two way ANOVA with repeated measures was used. In measuring the humoral immune response to the WNV component of the vaccine, results showed a significant (P < 0.05) increase in WNV IgG titers in vaccinated ponies compared to non-vaccinated saline controls. Measurement of CMI responses by flow cytometry showed a significant (P < 0.05) increase in the percentage of WNV-specific interferon-gamma producing cells from the vaccinated ponies compared to the saline controls. Measurement of WNV-specific CMI responses by RT-PCR showed a significant (P < 0.05) increase in WNV-specific interferon gamma and IL-2 gene expression in the vaccinated ponies compared to controls. There was no significant (P > 0.05) difference in the gene expression of GrzB, IL-6 or IL-18 when comparing the vaccinated ponies to the controls. Overall, the combination killed vaccine induced significant WNV-specific humoral and cell-mediated immune responses in na€ ıve animals. Infection control is crucial in the operation of all veterinary hospitals to not only protect the patients and hospital, but to protect personnel as those in the veterinary field have an increased risk of occupational exposure to zoonotic diseases. In a 2008 study, 50% of Veterinary Teaching Hospitals (VTHs) surveyed reported significant health problems due to zoonotic infections among hospital personnel. Cryptosporidium parvum infections accounted for 68% of these infections. The objective of this study was to characterize current infection control practices in place for the prevention of zoonotic disease infection, specifically infection of C. parvum, in VTHs.
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