2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018

No significant differences were identified between groups, within the saline group, and within the dexmedetomidine group for insulin, cortisol and lactate concentrations. Significant differences (P < 0.05) were observed within the dexmedetomidine group: increased blood glucose concentration at 60 min (11.55, [5.9-16.6] , mmol/L) and 120 min (12, [6.1-13.8 ], mmol/L) compared to t=0 (6.05, [4.8-13.3] , mmol/L); decreased serum glucagon concentration at 120 min (3.8, [2.7-8.8 ], pg/mL) and 180 min (4.7, [2.1-8.2] , pg/mL) compared to t=0 (11.85 This prospective study investigated the veracity of a recent retrospective study, where we found a significant negative correlation between serum total thyroxine (TT4) and glucose concentrations in cats. To that end, we used a naturally-occurring hyperthyroid cat model to determine the effect that a range of serum TT4 concentrations would have on serum glucose concentrations.