2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018

Parameters associated with malnutrition at the time of diagnosis of PLE due to CE or lymphangiectasia in dogs in this study were not a predictor of mortality following treatment failure and therefore cannot be used to predict response to treatment. However, alternative measures of malnutrition may be required to definitively investigate the role of malnutrition in the prognosis of canine PLE. Total FFA concentrations at baseline were not significantly increased in dogs with CE relative to healthy dogs (p = 0.099). The healthy canine FFA reference interval was found to be 12-26 mg/mg, and 44% (25/57) of dogs with CE had increased FFA (median ± SD, [minmax]: 66 ± 37 mg/mg, , p < 0.001). The FFA concentrations for these dogs after one month of treatment were significantly decreased (19 ± 35 mg/mg, , p < 0.001) and were no longer statistically different from the healthy dogs (p = 0.64), with 60% (15/25) no longer exceeding the healthy dog reference interval. Therefore, further analysis on the granulomatous gastritis in 11 MDs was performed.