2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018

Significant changes were observed in the fourth and tenth month of pregnancy for RR interval (1238.53 ± 100.37 ms; 962.60 ± 234.11 ms) and HR (49.42 ± 4.84 bpm; 62.43 ± 11 .53 bpm) (p = 0.018), corresponding to the smallest and largest value respectively. No significant changes were observed in the standard deviation of beat-to-beat interval (SDNN) (p = 0.466) or the root mean square of successive beat-to-beat differences (RMSSD) (p = 0.760). Time-domain analysis has demonstrated a significant increase in the mean RR intervals and HR with the progression of pregnancy and has also established that HRV is influenced by HR, as a higher HR was associated with a lower HRV in the mare. Renal dysfunction caused by primary cardiovascular disease is considered to be a class of cardiovascular renal disorders (CvRD). In small animal medicine, CvRD in cardiac patients is a novel research area. In this study we aimed to evaluate CvRD in cats with congestive heart failure (CHF) and primary cardiomyopathy (CM) by measuring cardiac and renal functional markers.