2016 ACVIM Forum Research Abstract Program

Results of this study validate that the new microtiter plate format ELISA is a highly specific, precise, and accurate method for detection of FeLV p27 antigen in feline patient samples and is appropriate for high-throughput applications in a reference laboratory setting. In small animal veterinary medicine, two of the most common pathogenic spirochete genera are Borrelia spp. and Leptospira spp.. While antibodies that develop against these organisms over the course of infection in dogs are thought to be genus specific, studies evaluating for cross-reactive antibodies against individual Borrelia spp. or Leptospira spp. peptides are for the most part lacking. The purpose of this study was to determine if Leptospira spp. antibodies induced by administration of one of four commercial vaccines would cross-react with the B. burgdorferi antigens used in a commercially available assay.