Title: 2016 ACVIM Forum Research Abstract Program Document date: 2016_5_31
ID: 2y1y8jpx_630
Snippet: After a 12 hour fast, each of 6 healthy cats received 15 mg/kg of posaconasole (NoxafilÃ’) oral suspension with food. Four cats also received 3 mg/kg IV posaconazole after a 7-day washout period. Plasma was collected at predetermined intervals for analysis using high pressure liquid chromatography (HPLC). Concentration data were analyzed using a two-compartment pharmacokinetic analysis for IV data and a one-compartment analysis with first-order i.....
Document: After a 12 hour fast, each of 6 healthy cats received 15 mg/kg of posaconasole (NoxafilÃ’) oral suspension with food. Four cats also received 3 mg/kg IV posaconazole after a 7-day washout period. Plasma was collected at predetermined intervals for analysis using high pressure liquid chromatography (HPLC). Concentration data were analyzed using a two-compartment pharmacokinetic analysis for IV data and a one-compartment analysis with first-order input for oral data using PhoenixÃ’ software (Certara).
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