2016 ACVIM Forum Research Abstract Program

In conclusion, plasma concentration of cTnI in dogs with stable CKD was not influenced by a decreased GFR. Plasma concentration of NT-proBNP in stable canine CKD patients on the other hand, appeared to be influenced by GFR. Studies have shown that normal healthy adult dogs may have occasional ventricular premature complexes (VPCs) and that more frequent or sequential VPCs on Holter monitoring may indicate cardiac or clinical disease. This poses a problem for cardiac evaluation of puppies for veterinarians. This lack of information inhibits the ability to screen puppies for indicators of cardiac disease. This is especially important in breeds that tend to have inherited cardiac arrhythmias such as German Shepherd puppies. The purpose of this study is to establish normal ambulatory ECG values using Holter monitors in puppies in an effort to enhance the ability to screen puppies for cardiac disease.