2016 ACVIM Forum Research Abstract Program

Although our study indicated that CTC crosses the placental barrier based on accumulation in the fetal kidney and liver, concentrations achieved were far below the minimum inhibitory concentrations (MIC) reported in the literature for isolates from abortion outbreaks and below our limit of quantification in amniotic fluid, fetal stomach contents and placenta. No studies demonstrate the concentrations of CTC that are preventative for abortion from Campylobacter spp.; our findings suggest that either the dosage used in this study is not high enough or that the pharmacodynamic parameter relating preventive dose to pathogen MICs is yet to be determined. Increased ketone bodies concentration in blood has been used to monitor goat during last month of pregnancy to diagnose animal with subclinical and/or clinical cases pregnancy toxemia (PT). Since clinical cases of PT are highly fatal, early diagnostic tool to predict mortality on farm would be useful to producer to save money on animal with lower chance of survival or to initiate more aggressive therapy depending on the value of the animal and its fetuses.