2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018

LA contractile dysfunction 24h after TVEC was detected in 5/6 horses based on active LA FAC and global S L . Active LA FAC did not change over time (p = 0.14) and remained below reference limits in 5/6 horses. Global S L significantly increased from 24h to 1mt after TVEC (p = 0.028); at that time, S L of all 6 horses was within (but at the lower range) of the reference interval. SR L was below the reference interval in 2/6 horses 24h after TVEC and within reference limits in all 6 horses 1mt after TVEC (p = 0.30). Strain and strain rate were significantly associated with active FAC (p2 adj =0.76 and p2 adj =0.77), passive FAC (p=0.016, R 2 adj =0.55 and p=0.016, R 2 adj =0.55), LAA max (p2 adj =0.85 and p2 adj =0.88), and LAD max (p2 adj =0.83 and p2 adj =0.85), with lower S L and SR L in larger atria.