2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018

The total median needle placement error for all 42 target points was 0.84 mm (range: 0.09-2.76; outlier: 4.11). The median needle placement error for the caudate nucleus only was 0.67 mm (range: 0.09-1.25) and for the piriform lobe 0.85 mm (range: 0.14-2.76). Therefore, the MRI-based patient-individual stereotactic brain biopsy device reaches higher accuracy than most other described brain biopsy systems. In SM dogs, the distance between the rostral end of the palate and i) sella turcica (P = 0.049) ii) foramen magnum basioccipital (P = 0.030) were significantly reduced, as was the maximum distance through the palate centroid (P = 0.015). However, the reduced distance between the brain and frontal bone was highly significant (P < 0.001). The reduction in distance between the olfactory bulb and the sella turcica may be of interest (P = 0.054). Discriminate analysis/logistic regression revealed that rostral skull flattening dominated any model but when removed, ratio of maximum distance through the palate centroid to cerebral height to cerebrum height was highly significant (P < 0.001).