Selected article for: "detection limit and inter assay variation"
Title: 2016 ACVIM Forum Research Abstract Program
  • Document date: 2016_5_31
    • ID: 2y1y8jpx_308
    Snippet: The lower limit of detection for citrulline in serum was 4.9 µmol/L. Observed-to-expected ratios for citrulline dilutional parallelism (n = 6) were 83.2% to 116.7%. Recoveries for spiking concentrations of citrulline in serum samples (n = 5) were between 84.9% to 119.4%. Mean intra-and inter-assay coefficients of variation (%CVs) for the citrulline assay were 5.4% and 10.9%, respectively. Dogs with chronic enteropathy had significantly lower ser.....
    Document: The lower limit of detection for citrulline in serum was 4.9 µmol/L. Observed-to-expected ratios for citrulline dilutional parallelism (n = 6) were 83.2% to 116.7%. Recoveries for spiking concentrations of citrulline in serum samples (n = 5) were between 84.9% to 119.4%. Mean intra-and inter-assay coefficients of variation (%CVs) for the citrulline assay were 5.4% and 10.9%, respectively. Dogs with chronic enteropathy had significantly lower serum citrulline concentrations (median [minimum -maximum]: 10.5 µmol/L [2.8 -46.0]) than healthy dogs (median [minimummaximum] 32.5 µmol/L [20.0 -44.0]; P < 0.0001).

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