Author: Hayward, Gail; Thompson, Matthew; Heneghan, Carl; Perera, Rafael; Del Mar, Chris; Glasziou, Paul
Title: Corticosteroids for pain relief in sore throat: systematic review and meta-analysis Document date: 2009_8_6
ID: 67bhdlzy_23
Snippet: The direction of effect for mean time to onset of pain relief was similar in trials with adults only, in trials with intramuscular and oral routes of steroid administration, and in trials in which severe sore throat was not selected. The effect on children only, those with less than 50% exudative sore throat, and non-bacterial pathogen positive only did not reach significance .We did not find significant changes in mean time to onset of pain reli.....
Document: The direction of effect for mean time to onset of pain relief was similar in trials with adults only, in trials with intramuscular and oral routes of steroid administration, and in trials in which severe sore throat was not selected. The effect on children only, those with less than 50% exudative sore throat, and non-bacterial pathogen positive only did not reach significance .We did not find significant changes in mean time to onset of pain relief in trials with children only, trials with less than 50% exudative sore throat, and in the subgroup of patients with sore throat not positive for bacterial pathogens. Meta-regression analysis revealed no significant differences across all subgroups (fig 4).
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